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Clozapine-Paliperidone LA

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There are 2 switch possibities:

Number 1 (the general approach):

Oral risperidone has better and more stable bioavailability properties than has oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.


Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):

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