Metabolization is defined within this context as a property of a drug, and will be displayed on combination pages. Text
Pages using the property "Metabolization"
Showing 11 pages using this property.
|Aripiprazole +||*Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.|
|Carbamazepine +||* Carbamazepine is principally metabolized by CYP3A4, and is a potent inducer of CYP1A2, CYP2C9, CYP3A4 and UDP-glucuronosyltransferases.|
|Gabapentin +||* Gabapentin is eliminated unchanged by the kidney for 100%.|
|Lamotrigine +||* Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.|
|Lithium +||* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.|
|Olanzapine +||* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.|
|Quetiapine +||* Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.|
|Risperidone +||* Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone).|
|Topiramate +||* Topiramate induces CYP3A4 and is an inhibitor of CYP2C19.|
|Valproic acid +||* Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.|
|Ziprasidone +||* Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.|