Agomelatine-tranylcypromine

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Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from agomelatine to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop agomelatine
  • Agomelatine can be stopped abruptly for every dosage.
Eenrichtingbord.png Start tranylcypromine
  • No wash-out period is necessary.
  • Start administration of tranylcypromine the next day in a normal dosage of 20 mg/day.
  • If necessary, increase the dosage of tranylcypromine.

[3]


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102
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