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Bupropion-amitriptyline

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| to = amitriptyline  
| to = amitriptyline  
| stop =  
| stop =  
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* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.  
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* '''Before day 1:''' Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.
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* When a dosage of 150 mg/day is reached, stop administration.
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* '''Day 1:''' Stop administration of bupropion
| start =   
| start =   
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* '''Day 1-3:''' start administration of amitriptyline the next day in a low dosage of 25 mg/day.
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* '''Day 1-3:''' start administration of amitriptyline in a low dosage of 25 mg/day.
* '''Day 4:''' increase dosage of amitriptyline to 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
* '''Day 4:''' increase dosage of amitriptyline to 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
| info =   
| info =   
* Bupropion slows the metabolism of amitriptyline via CYP2D6.
* Bupropion slows the metabolism of amitriptyline via CYP2D6.
* Caution is necessary at the start of administration of amitriptyline. }}
* Caution is necessary at the start of administration of amitriptyline. }}

Revision as of 12:09, 1 September 2009

Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline

Switch medication from bupropion to amitriptyline.

Nietinrijdenbord.png Stop bupropion
Eenrichtingbord.png Start amitriptyline
Infobord.png More information
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