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Bupropion-venlafaxine

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* By considering a wash-out period of one week (5 times the elimination time of bupropion and its metabolites) it is assured that all bupropion has left the body and no drug interactions occur.  
* By considering a wash-out period of one week (5 times the elimination time of bupropion and its metabolites) it is assured that all bupropion has left the body and no drug interactions occur.  
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* Bupropion slows the metabolism of venlafaxine by CYP2D6.<ref> Stöllberger C, Huber JO, Finsterer J, [http://www.ncbi.nlm.nih.gov/pubmed/16096514?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Antipsychotic drugs and QT prolongation]. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.</ref>
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* Bupropion slows the metabolism of venlafaxine by CYP2D6.<ref> Kennedy et al, [http://www.ncbi.nlm.nih.gov/pubmed/11926715?ordinalpos=11&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Antipsychotic drugs and QT prolongation]. J Clin Psychiatry 2002 March;63(3):181-6.</ref>
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Revision as of 13:04, 1 September 2009

Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine

Switch medication from bupropion to venlafaxine.

Nietinrijdenbord.png Stop bupropion
Eenrichtingbord.png Start venlafaxine
Infobord.png More information
  1. Kennedy et al, Antipsychotic drugs and QT prolongation. J Clin Psychiatry 2002 March;63(3):181-6.
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