Difference between revisions of "Citalopram-doxepine"

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| to = doxepin
 
| to = doxepin
 
| stop =  
 
| stop =  
* '''Day 0:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.  
+
* '''Before day 1:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.  
 
* '''Day 1:''' reduce dosage of citalopram/escitalopram to a maximum of 10 mg/ day resp. 5 mg/day.  
 
* '''Day 1:''' reduce dosage of citalopram/escitalopram to a maximum of 10 mg/ day resp. 5 mg/day.  
 
* '''Day 8:''' stop administration of citalopram/escitalopram.
 
* '''Day 8:''' stop administration of citalopram/escitalopram.

Revision as of 15:12, 11 September 2009

Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Doxepin
Type antidepressant
Group TCA
links
ATC-code N06AA12
Medscape Doxepin
PubChem 3158
PubMed Doxepin
Drugs.com doxepin
Kompas (Dutch) Doxepin
Wikipedia Doxepin

Switch medication from citalopram to doxepin.[2] [3]

Nietinrijdenbord.png Stop citalopram
  • Before day 1: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
  • Day 1: reduce dosage of citalopram/escitalopram to a maximum of 10 mg/ day resp. 5 mg/day.
  • Day 8: stop administration of citalopram/escitalopram.
Eenrichtingbord.png Start doxepin
  • Day 8: start administration of doxepin in a normal dosage of 25 mg/day.
  • Day 15: increase dosage of doxepin.
Infobord.png More information
  • The same applies to escitalopram.
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. 1.0 1.1 1.2 1.3 1.4 KNMP; Informatorium Medicamentorum 2023; Monografie "doxepine" (Dutch)
  2. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  3. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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