Citalopram-tranylcypromine

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Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from citalopram to tranylcypromine.

Nietinrijdenbord.png Stop citalopram
  • Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
  • Day 1: Reduce dosage of citalopram/escitalopram to a maximum of 10 mg/ day resp. 5 mg/day.
  • Day 8: stop administration of citalopram/escitalopram.
Eenrichtingbord.png Start tranylcypromine
  • Day 8-21: a wash-out period of two weeks is necessary.
  • Day 22: Start administration of tranylcypromine in low dosage of 20 mg/day for one week.
  • Day 29: after this week the dosage of tranylcypromine can be increased if necessary.
Letopbord.png Cave
  • Occurrence of serotonin syndrome is reported when a wash-out period (of two weeks) is not considered.


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