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Clomipramine-citalopram

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* '''Before day 1:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/day.
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{{stopClomipramine}}
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* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.
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* '''Day 3:''' reduce dosage of clomipramine to 10 mg/day.
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* '''Day 8:''' stop administration of clomipramine.
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* '''Day 1:''' simultaneously start administration of citalopram in a normal dosage of 20 mg/day.
* '''Day 1:''' simultaneously start administration of citalopram in a normal dosage of 20 mg/day.
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* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
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* {{theorSS}}
* Citalopram is a very weak inhibitor of CYP2D6, which metabolizes clomipramine.
* Citalopram is a very weak inhibitor of CYP2D6, which metabolizes clomipramine.
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{{review}}
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Current revision as of 10:57, 4 November 2015

Clomipramine
Type Antidepressant
Group TCA
links
ATC-code N06AA04
Medscape Clomipramine
PubChem 2801
PubMed Clomipramine
Kompas (Dutch) Clomipramine
Wikipedia Clomipramine
Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram

Switch medication from clomipramine to citalopram.

Nietinrijdenbord.png Stop clomipramine
Eenrichtingbord.png Start citalopram
Infobord.png More information
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