Difference between revisions of "Clozapine-Lurasidone"

From Psychiatrienet
Jump to: navigation, search
Line 3: Line 3:
 
| to = Lurasidon
 
| to = Lurasidon
 
| stop =  
 
| stop =  
* '''Day 1:''' gradually reduce the dose of haloperidol with 12,5-25 mg a week <ref>[http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1415944617205.pdf MHRA. SmPC Clozaril 100 mg tablets.]</ref>
+
* '''Day 1:''' gradually reduce the dose of clozapine with 25 mg / 2 days <ref>[http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1415944617205.pdf MHRA. SmPC Clozaril 100 mg tablets.]</ref>
 
| start =  
 
| start =  
 
* '''Week 1:''' approx. 25% of target dose  
 
* '''Week 1:''' approx. 25% of target dose  
Line 9: Line 9:
 
* '''Week 3:''' approx. 75% of target dose
 
* '''Week 3:''' approx. 75% of target dose
 
* '''Week 4:''' target dose   
 
* '''Week 4:''' target dose   
| info = {{ClozEffect}} {{caveQT}}
+
| info = {{ClozEffect}}
 
}}
 
}}

Revision as of 15:18, 16 March 2015

Clozapine
Type Antipsychotic
Group Atypical AP
links
Medscape Clozapine
PubChem 2818
PubMed Clozapine
Kompas (Dutch) Clozapine
Wikipedia Clozapine
Lurasidone
Type Antipsychotic
Group Atypical AP
links
Medscape Lurasidone
PubMed Lurasidone
Kompas (Dutch) Lurasidone
Wikipedia Lurasidone

Switch medication from Clozapine to Lurasidon.

Nietinrijdenbord.png Stop Clozapine
  • Day 1: gradually reduce the dose of clozapine with 25 mg / 2 days [1]
Eenrichtingbord.png Start Lurasidon
  • Week 1: approx. 25% of target dose
  • Week 2: approx. 50% of target dose
  • Week 3: approx. 75% of target dose
  • Week 4: target dose
Infobord.png More information
  • Clozapine is generally considered to be more effective than other antipsychotic drugs. Clozapine is often used in treatment-resistant schizophrenia (poor treatment response to 2 or more antipsychotic drugs). So a switch from clozapine to another antipsychotic drug could cause problems regarding effectiveness.[2] [3] [4]
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.