Difference between revisions of "Combining-Ziprasidone-Lamotrigine"

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* Start lamotrigine according to the general dosing advice.
 
* Start lamotrigine according to the general dosing advice.
 
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* Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom">
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* Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscomint">
 
{{Drugscominteract|ziprasidone-with-lamotrigine-2330-0-1430-0|ziprasidone|lamotrigine}}</ref>   
 
{{Drugscominteract|ziprasidone-with-lamotrigine-2330-0-1430-0|ziprasidone|lamotrigine}}</ref>   
 
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Revision as of 13:07, 15 June 2010

Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone
Lamotrigine
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AX09
PubChem 3878
PubMed Lamotrigine
Drugs.com lamotrigine
Kompas (Dutch) Lamotrigine
Wikipedia Lamotrigine

Adding lamotrigine to ziprasidone.

Infobord.png General information
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
  • Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.[4]
  • This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. [5]
Eenrichtingbord.png Start lamotrigine
  • Start lamotrigine according to the general dosing advice.
Letopbord.png Cave
  • Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. [6]


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