Difference between revisions of "Combining-Ziprasidone-Olanzapine"

From Psychiatrienet
Jump to: navigation, search
(Created page with '{{Drugcombi | base = ziprasidone | add = olanzapine | info = * There is no evidence published related to this drug combination recently. The combination will have additive side...')
 
 
Line 2: Line 2:
 
| base = ziprasidone
 
| base = ziprasidone
 
| add = olanzapine
 
| add = olanzapine
| info =  
+
| info =   
* There is no evidence published related to this drug combination recently. The combination will have additive side effects.
 
 
| start =  
 
| start =  
* Start olanzapine according to the general dosing advice.
+
{{IrrationalCombiAP}}
 
| cave =  
 
| cave =  
 
* Agents with anticholinergic properties may have additive effects when used in combination. <ref name="drugscom">
 
* Agents with anticholinergic properties may have additive effects when used in combination. <ref name="drugscom">
 
{{Drugscominteract|ziprazidone-with-olanzapine-2330-0-1744-0|ziprazidone|olanzapine}}</ref>   
 
{{Drugscominteract|ziprazidone-with-olanzapine-2330-0-1744-0|ziprazidone|olanzapine}}</ref>   
 
}}
 
}}

Latest revision as of 10:35, 25 June 2010

Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone
Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine

Adding olanzapine to ziprasidone.

Infobord.png General information
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
Eenrichtingbord.png Start olanzapine
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Letopbord.png Cave
  • Agents with anticholinergic properties may have additive effects when used in combination. [4]


  1. 1.0 1.1 1.2 1.3 KNMP; Informatorium Medicamentorum 2023; Monografie "olanzapine" (Dutch)
  2. Farmacotherapeutisch Kompas; Toxicologie (dutch)
  3. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667
  4. Interactions between ziprazidone and olanzapine on drugs.com
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.