Difference between revisions of "Dosulepine-tranylcypromine"

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* '''Day 8-21:''' a wash-out period of two weeks is necessary.
 
* '''Day 8-21:''' a wash-out period of two weeks is necessary.
 
* '''Day 22:''' start administration of tranylcypromine in a low dosage of 20 mg/day for one week.
 
* '''Day 22:''' start administration of tranylcypromine in a low dosage of 20 mg/day for one week.
* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary.}}
+
* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary.
 +
|info=
 +
{{review}}
 +
}}

Revision as of 15:11, 28 October 2015

dosulepin
Type antidepressant
Group TCA
links
ATC-code N06AA16
PubChem 13473
PubMed dosulepin
Kompas (Dutch) dosulepin
Wikipedia dosulepin
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from dosulepine to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop dosulepine
  • Before day 1: gradually reduce dosage of dosulepine to a maximum of 75 mg/ day, when this dosage is > 75 mg/day.
  • Day 1-3: reduce dosage of dosulepine to 50 mg/day.
  • Day 4-7: reduce dosage of dosulepine to 25 mg/day.
  • Day 8: stop administration of dosulepine.
Eenrichtingbord.png Start tranylcypromine
  • Day 8-21: a wash-out period of two weeks is necessary.
  • Day 22: start administration of tranylcypromine in a low dosage of 20 mg/day for one week.
  • Day 29: after this week the dosage of tranylcypromine can be increased if necessary.
Infobord.png More information
  • This switch is currently being reviewed.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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