Difference between revisions of "Dosulepine-trazodone"

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* '''Day 8:''' stop administration of dosulepine .
 
* '''Day 8:''' stop administration of dosulepine .
 
| start =  
 
| start =  
* '''Day 9:''' simultaneously start administration of trazodone in a dosage of 100-150 mg/day.
+
* '''Day 9:''' start administration of trazodone in a dosage of 100-150 mg/day.
 
* '''Day 16:''' increase administration of trazodone.  
 
* '''Day 16:''' increase administration of trazodone.  
 
| info =  
 
| info =  
 
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.}}
 
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.}}

Revision as of 10:28, 2 April 2010

dosulepin
Type antidepressant
Group TCA
links
ATC-code N06AA16
PubChem 13473
PubMed dosulepin
Kompas (Dutch) dosulepin
Wikipedia dosulepin
Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone

Switch medication from dosulepine to trazodone.[1] [2]

Nietinrijdenbord.png Stop dosulepine
  • Before day 1: gradually reduce dosage of dosulepine to a maximum of 75 mg/ day, when this dosage is > 75 mg/day.
  • Day 1: reduce dosage of dosulepine to 25 mg/day.
  • Day 8: stop administration of dosulepine .
Eenrichtingbord.png Start trazodone
  • Day 9: start administration of trazodone in a dosage of 100-150 mg/day.
  • Day 16: increase administration of trazodone.
Infobord.png More information
  • Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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