Difference between revisions of "Doxepine-duloxetine"

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| to = duloxetine
 
| to = duloxetine
 
| stop =  
 
| stop =  
* '''Before day 1:''' gradually reduce dosage of doxepin to a maximum of 100 mg/day.
+
{{downDoxepin}}
* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.
 
* '''Day 3:''' reduce dosage of doxepin to 25 mg/day.
 
* '''Day 8:''' stop administration of doxepin.
 
 
| start =  
 
| start =  
* '''Day 8:''' start administration of duloxetine in a dosage of 30 mg/day.
+
* '''Day 9:''' start administration of duloxetine in a dosage of 30 mg/day.
* '''Day 15:''' increase administration of duloxetine to 60 mg.
+
* '''Day 16:''' increase administration of duloxetine to 60 mg.
 
| info =  
 
| info =  
 
* Duloxetine is an inhibitor of CYP2D6, which metabolizes doxepin.
 
* Duloxetine is an inhibitor of CYP2D6, which metabolizes doxepin.
{{review}}
 
 
}}
 
}}

Latest revision as of 14:40, 2 November 2015

Doxepin
Type antidepressant
Group TCA
links
ATC-code N06AA12
Medscape Doxepin
PubChem 3158
PubMed Doxepin
Drugs.com doxepin
Kompas (Dutch) Doxepin
Wikipedia Doxepin
Duloxetine
Type Antidepressant
Group SNRI
links
Medscape Duloxetine
PubChem 60835
PubMed Duloxetine
Kompas (Dutch) Duloxetine
Wikipedia Duloxetine

Switch medication from doxepin to duloxetine.

Nietinrijdenbord.png Stop doxepin
  • Before day 1: gradually reduce dosage of doxepin to a maximum of 100 mg/day.
  • Day 1: reduce dosage of doxepin to 50 mg/day.
  • Day 3: reduce dosage of doxepin to 25 mg/day.
  • Day 8: stop administration of doxepin.
Eenrichtingbord.png Start duloxetine
  • Day 9: start administration of duloxetine in a dosage of 30 mg/day.
  • Day 16: increase administration of duloxetine to 60 mg.
Infobord.png More information
  • Duloxetine is an inhibitor of CYP2D6, which metabolizes doxepin.
  1. 1.0 1.1 1.2 1.3 1.4 KNMP; Informatorium Medicamentorum 2015; Monografie "doxepine" (Dutch)
  2. NVZA; Toxicology.org; Monografie 63 (dutch)
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