Difference between revisions of "Doxepine-moclobemide"

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Revision as of 16:46, 28 October 2015

Type antidepressant
Group TCA
ATC-code N06AA12
Medscape Doxepin
PubChem 3158
PubMed Doxepin
Drugs.com doxepin
Kompas (Dutch) Doxepin
Wikipedia Doxepin
Type Antidepressant
Group MAO-I
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from doxepin to moclobemide.

Nietinrijdenbord.png Stop doxepin
  • Before day 1: gradually reduce dosage of doxepin to a maximum of 100 mg/day.
  • Day 1: reduce dosage of doxepin to 50 mg/day.
  • Day 8: reduce dosage of doxepin to 25 mg/day.
  • Day 15: stop administration of doxepin.
Eenrichtingbord.png Start moclobemide
  • Day 15-28: a wash-out period of 2 weeks is necessary.
  • Day 29 start administration of moclobemide in a dosage of 150 mg/day.
  • Day 35: increase dosage of moclobemide to 300 mg/day.
Letopbord.png Cave
Infobord.png More information
  • This switch is currently being reviewed.
  1. 1.0 1.1 1.2 1.3 1.4 KNMP; Informatorium Medicamentorum 2015; Monografie "doxepine" (Dutch)
  2. NVZA; Toxicology.org; Monografie 63 (dutch)
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