Difference between revisions of "Escitalopram-fluvoxamine"

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| from = escitalopram
 
| from = escitalopram
 
| to = fluvoxamine
 
| to = fluvoxamine
| stop = {{StopEscitalopramAtDose}}
+
| stop = {{StopEscitalopram}}
 
| start =  
 
| start =  
 
* No wash-out period is needed.
 
* No wash-out period is needed.
* Start fluvoxamine the next day in normal dosage of 50 mg/day.
+
* '''Day 9: '''start fluvoxamine in normal dosage of 50 mg/day.
 
| info =  
 
| info =  
 
* {{theorSS}}
 
* {{theorSS}}
 
* Fluvoxamine slows the metabolism of escitalopram by inhibition of CYP2C19 and CYP3A4
 
* Fluvoxamine slows the metabolism of escitalopram by inhibition of CYP2C19 and CYP3A4
{{review}}
 
 
}}
 
}}

Latest revision as of 09:58, 28 October 2015

Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram
Fluvoxamine
Type Antidepressant
Group SSRI
links
Medscape Fluvoxamine
PubChem 5324346
PubMed Fluvoxamine
Kompas (Dutch) Fluvoxamine
Wikipedia Fluvoxamine

Switch medication from escitalopram to fluvoxamine.

Nietinrijdenbord.png Stop escitalopram
  • Before day 1: gradually reduce dosage of escitalopram to a maximum of 10 mg/day, when this dosage is >10 mg/day.
  • Day 1: reduce dosage of escitalopram to a maximum of 5 mg/day.
  • Day 8: stop administration of escitalopram.
Eenrichtingbord.png Start fluvoxamine
  • No wash-out period is needed.
  • Day 9: start fluvoxamine in normal dosage of 50 mg/day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  • Fluvoxamine slows the metabolism of escitalopram by inhibition of CYP2C19 and CYP3A4
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