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Fluoxetine-doxepine

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| from = fluoxetine  
| from = fluoxetine  
| to = doxepin
| to = doxepin
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| stop =  
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|stop =  
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* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day.
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{{stopFluoxetine1}}
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* When a dosage of 20 mg/day is reached, stop administration.
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|start =  
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| start =  
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Caution is necessary for at least four weeks.
Caution is necessary for at least four weeks.
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* '''Day 1:''' start administration of doxepin in a low dosage of 25 mg/day.
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* '''Day 2:''' start administration of doxepin in a low dosage of 25 mg/day.
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* '''Day 14:''' increase dosage of doxepin to 50 mg/day.
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* '''Day 15:''' increase dosage of doxepin to 50 mg/day.
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* '''Day 28:''' increase dosage of doxepin to 75 mg/day.
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* '''Day 29:''' increase dosage of doxepin to 75 mg/day.
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| info =   
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|info =   
* Fluoxetine and norfluoxetine slow the metabolism of doxepin via CYP2D6.  
* Fluoxetine and norfluoxetine slow the metabolism of doxepin via CYP2D6.  
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* Norfluoxetine has a halflife of at least 1 week: it takes therefore 1 month for elemination.
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{{longt1/2fluvox}}
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* Start low, go slow for doxepin.
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* Start low, go slow for doxepin.}}
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{{review}}}}
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Current revision as of 12:44, 28 October 2015

Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine
Doxepin
Type antidepressant
Group TCA
links
ATC-code N06AA12
Medscape Doxepin
PubChem 3158
PubMed Doxepin
Drugs.com doxepin
Kompas (Dutch) Doxepin
Wikipedia Doxepin

Switch medication from fluoxetine to doxepin.

Nietinrijdenbord.png Stop fluoxetine
Eenrichtingbord.png Start doxepin

Caution is necessary for at least four weeks.

Infobord.png More information
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