Difference between revisions of "Fluoxetine-tranylcypromine"

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* Desmethylfluoxetine has a half live of about one week so a long wash-out period is necessary.
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* Norfluoxetine has a half live of about one week so a long wash-out period is necessary.
 
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Revision as of 13:11, 20 June 2016

Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from fluoxetine to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop fluoxetine
  • Decrease with about 25% of original dose every 3 days
  • wait for 5-6 weeks for washout
Eenrichtingbord.png Start tranylcypromine
  • Start at the first day after the washout period of 5-6 weeks with about 25% of target dose.
Letopbord.png Cave
Infobord.png More information
  • Norfluoxetine has a half live of about one week so a long wash-out period is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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