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Imipramine-citalopram

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* '''Day 1:''' reduce dosage of imipramine to 50 mg/day.
* '''Day 1:''' reduce dosage of imipramine to 50 mg/day.
* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.
* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.
 +
* '''Day 8:''' stop administration of imipramine.
| start =  
| start =  
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* '''Day 1:''' simultaneously start administration of citalopram/escitalopram in a normal dosage of 20 mg/day, resp. 10 mg/day.
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* '''Day 1:''' simultaneously start administration of citalopram in a normal dosage of 20 mg/day.
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* '''Day 8:''' stop administration of imipramine and continue administration of citalopram/escitalopram.
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| info =  
| info =  
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
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* Citalopram/escitalopram are a weak inhibitor of CYP2D6, which metabolizes imipramine.   
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* Citalopram is a weak inhibitor of CYP2D6, which metabolizes imipramine.   
* {{theorSS}}
* {{theorSS}}
}}
}}

Revision as of 22:34, 4 March 2010

Imipramine
Type Antidepressant
Group TCA
links
Medscape Imipramine
PubChem 3696
PubMed Imipramine
Kompas (Dutch) Imipramine
Wikipedia Imipramine
Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram

Switch medication from imipramine to citalopram.

Nietinrijdenbord.png Stop imipramine
Eenrichtingbord.png Start citalopram
Infobord.png More information
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