Mianserine-hypericum

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Mianserine
Type Antidepressant
Group other
links
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine
Hypericum
Type Antidepressant
Group other
links
EMEA 10130408en
PubMed Hypericum
Kompas (Dutch) hypericum extract
Wikipedia St John's wort

Switch medication from mianserine to hypericum.[1] [2]

Nietinrijdenbord.png Stop mianserine
  • Before day 1: gradually reduce dosage of mianserine to a maximum of 60 mg/day, when this dosage is > 60 mg/day.
  • Day 1: reduce dosage of mianserine to 30 mg/day.
  • Day 8: stop administration of mianserine.
Eenrichtingbord.png Start hypericum
  • Day 8-14: a wash-out period of one week is necessary.
  • Day 15: start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).[3][4][5][6]
Infobord.png More information
  • Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
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