Difference between revisions of "Mirtazapine-nortriptyline"

From Psychiatrienet
Jump to: navigation, search
(Undo revision 7506 by Anoek (talk))
Line 3: Line 3:
 
| to = nortriptyline  
 
| to = nortriptyline  
 
| stop =  
 
| stop =  
* '''Before day 1:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.
+
{{stopMirtazapine}}
* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.
 
 
| start =
 
| start =
No wash-out period is needed.
+
 
* '''Day 1:''' simultaneously start administration of nortriptyline in a dosage of 50 mg/day.  
+
{{Inc25p3d2}}
* '''Day 8:''' stop administration of mirtazapine and continue administration of nortriptyline. If necessary, increase dosage of nortriptyline.
+
* Start administration of nortriptyline in a dosage of 50 mg/day.  
* "Start low, go slow" is not required, but caution is necessary.
+
 
 +
 
  
 
| info =
 
| info =
{{review}}
+
* No wash-out period is needed.
 +
* "Start low, go slow" is not required, but caution is necessary.
 
}}
 
}}

Revision as of 10:47, 14 October 2015

Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine
Nortriptyline
Type Antidepressant
Group TCA
links
Medscape Nortriptyline
PubChem 4543
PubMed Nortriptyline
Kompas (Dutch) Nortriptyline
Wikipedia Nortriptyline

Switch medication from mirtazapine to nortriptyline.[1] [2]

Nietinrijdenbord.png Stop mirtazapine
  • Before day 1: Gradually reduce dosage of mirtazapine to a maximum of 30 mg/day, when this dosage is > 30 mg/day.
  • Day 1: Reduce dosage of mirtazapine to 15 mg/day.
  • Day 8: Stop administration of mirtazapine.
Eenrichtingbord.png Start nortriptyline
  • Day 2: Start with normal dosage and increase with about 25% (up to 50%) every 3 days to target dose.
  • Start administration of nortriptyline in a dosage of 50 mg/day.
Infobord.png More information
  • No wash-out period is needed.
  • "Start low, go slow" is not required, but caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.