Moclobemide-clomipramine

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Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Clomipramine
Type Antidepressant
Group TCA
links
ATC-code N06AA04
Medscape Clomipramine
PubChem 2801
PubMed Clomipramine
Kompas (Dutch) Clomipramine
Wikipedia Clomipramine

Switch medication from moclobemide to clomipramine.

Nietinrijdenbord.png Stop moclobemide
  • Decrease with about 25% of original dose every 3 days
Eenrichtingbord.png Start clomipramine
  • Start with the initial dose
Infobord.png More information
  • Because of the short half life of moclobemide (approx. 2h), the next antidepressant can start next day after stopping with moclobemide.[1]
  • Start low, go slow.
  1. Keks, Nicholas, J. Hope, and S. Keogh. "Switching and stopping antidepressants." Australian Prescriber 39.3 (2016).
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