Difference between revisions of "Moclobemide-escitalopram"

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#redirect [[Moclobemide-citalopram]]
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{{Drugswitch
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| from = moclobemide
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| to = escitalopram
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| stop =
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* '''Before day 1:''' gradually reduce dosage of moclobemide to a maximum of 300 mg/day.
 +
* '''Day 1:''' reduce the dosage of moclobemide to 150 mg/day.
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* '''Day 8:''' stop administration of moclobemide.
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| start = 
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* '''Day 8-9:''' a wash-out period of two days is necessary.
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* '''Day 10:''' start escitalopram after this period in a normal dosage of 10 mg/day.
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| info =
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* Caution is necessary, because occurrence of the serotonin syndrome is theoretically possible.
 +
}}

Revision as of 23:44, 4 March 2010

Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram

Switch medication from moclobemide to escitalopram.[1] [2]

Nietinrijdenbord.png Stop moclobemide
  • Before day 1: gradually reduce dosage of moclobemide to a maximum of 300 mg/day.
  • Day 1: reduce the dosage of moclobemide to 150 mg/day.
  • Day 8: stop administration of moclobemide.
Eenrichtingbord.png Start escitalopram
  • Day 8-9: a wash-out period of two days is necessary.
  • Day 10: start escitalopram after this period in a normal dosage of 10 mg/day.
Infobord.png More information
  • Caution is necessary, because occurrence of the serotonin syndrome is theoretically possible.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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