Difference between revisions of "Nortriptyline-imipramine"

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| to = imipramine  
 
| to = imipramine  
 
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| stop =  
* {{downNortriptyline}}
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{{downNortriptyline}}
 
| start =  
 
| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  

Revision as of 14:22, 2 November 2015

Nortriptyline
Type Antidepressant
Group TCA
links
Medscape Nortriptyline
PubChem 4543
PubMed Nortriptyline
Kompas (Dutch) Nortriptyline
Wikipedia Nortriptyline
Imipramine
Type Antidepressant
Group TCA
links
Medscape Imipramine
PubChem 3696
PubMed Imipramine
Kompas (Dutch) Imipramine
Wikipedia Imipramine

Switch medication from nortriptyline to imipramine.[1] [2]

Nietinrijdenbord.png Stop nortriptyline
  • Day 1: reduce dosage to 50%.
  • Day 8: stop
Eenrichtingbord.png Start imipramine
  • No wash-out period is needed.
  • Day 9: start administration of imipramine in a normal dosage of 50-100 mg/day.
Infobord.png More information
  • Both drugs are a TCA with anticholinergic properties, so a switch to a relatively high starting dose can be made.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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