Paliperidone LA-Sulpiride

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Paliperidone
long acting
Type Antipsychotic
Group Atypical AP
links
Medscape Paliperidone
PubChem 23724979
PubMed Paliperidone
Kompas (Dutch) Paliperidone
Wikipedia Paliperidone
Sulpiride
Type Antipsychotic
Group Atypical AP
links
PubChem 5355
PubMed Sulpiride
Kompas (Dutch) Sulpiride
Wikipedia Sulpiride

Switch medication from Paliperidone LA to Sulpiride.

Nietinrijdenbord.png Stop Paliperidone LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Sulpiride
  • Day 31-34: approx. 25% of target dose
  • Day 35-38: approx. 50% of target dose
  • Day 39-42: approx. 75% of target dose
  • Day 43: target dose
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[1]
    Stopdepotstartafter30days.png
Nietinrijdenbord.png — Paliperidone LA
Eenrichtingbord.png — Sulpiride


  1. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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