Difference between revisions of "Paroxetine-venlafaxine"

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| to = venlafaxine  
 
| to = venlafaxine  
 
| stop =  
 
| stop =  
{{downparox}}
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{{stopParoxetine}}
 
| start =  
 
| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* {{startVenla}}
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* ''' Day 9: '''{{startVenla}}
 
| info =
 
| info =
* Occurrence of the serotonin syndrome is theoretically possible.
+
* {{theorSS}}
 
* Paroxetine slows the metabolism of venlafaxine via CYP2D6.
 
* Paroxetine slows the metabolism of venlafaxine via CYP2D6.
{{review}}
 
 
}}
 
}}

Latest revision as of 15:52, 28 October 2015

paroxetine
Type Antidepressant
Group SSRI
links
Medscape paroxetine
PubChem 43815
PubMed paroxetine
Kompas (Dutch) paroxetine
Wikipedia paroxetine
Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine

Switch medication from paroxetine to venlafaxine.

Nietinrijdenbord.png Stop paroxetine
  • Before day 1: gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day.
  • Day 1: reduce dosage of paroxetine to a maximum of 10 mg/day.
  • Day 8: stop administration of paroxetine.
Eenrichtingbord.png Start venlafaxine
  • No wash-out period is needed.
  • Day 9: Start administration of venlafaxine in a normal dosage of 37,5 mg or 75 mg (slow release) /day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  • Paroxetine slows the metabolism of venlafaxine via CYP2D6.
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