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Sertraline-amitriptyline

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(Created page with '{{Drugswitch | from = sertraline | to = amitriptyline | stop = * '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/day when this dosage is > 50 mg/day....')
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| stop =  
| stop =  
* '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/day when this dosage is > 50 mg/day.  
* '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/day when this dosage is > 50 mg/day.  
-
* '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day.  
+
* '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day.
 +
* '''Day 8:''' stop administration of sertraline.  
| start =  
| start =  
Caution is necessary.
Caution is necessary.
* '''Day 1:''' simultaneously start administration of amitriptyline in a low dosage of 25 mg/day.  
* '''Day 1:''' simultaneously start administration of amitriptyline in a low dosage of 25 mg/day.  
-
* '''Day 8:''' stop administration of sertraline and only continue administration of amitriptyline in a dosage of 50 mg/day.
+
* '''Day 8:''' continue administration of amitriptyline in a dosage of 50 mg/day.
* Start low, go slow!
* Start low, go slow!
| info =  
| info =  
* Sertraline dose-dependently slows the metabolism of amitriptyline via CYP2D6. }}
* Sertraline dose-dependently slows the metabolism of amitriptyline via CYP2D6. }}

Revision as of 11:08, 24 June 2009

Sertraline
Type Antidepressant
Group SSRI
links
Medscape Sertraline
PubChem 68617
PubMed Sertraline
Kompas (Dutch) Sertraline
Wikipedia Sertraline
Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline

Switch medication from sertraline to amitriptyline.

Nietinrijdenbord.png Stop sertraline
Eenrichtingbord.png Start amitriptyline

Caution is necessary.

Infobord.png More information
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