Difference between revisions of "Stop-venlafaxine"

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| from = venlafaxine
 
| from = venlafaxine
 
| stop = {{StopAlgemeen}}
 
| stop = {{StopAlgemeen}}
* 150 mg/day <ref>{{Pubmed|9396960|Fava M et al. Emergence of adverse events following discontinuation of treatment with extended-release venlafaxine. Am J Psychiatry. 1997 Dec;154(12):1760-2}}</ref><ref>{{Pubmed|11347722|Haddad PM. Antidepressant discontinuation syndromes. Drug Saf. 2001;24(3):183-97}}</ref>:
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* 150 mg/day {{refBazire}}<ref>{{Pubmed|9396960|Fava M et al. Emergence of adverse events following discontinuation of treatment with extended-release venlafaxine. Am J Psychiatry. 1997 Dec;154(12):1760-2}}</ref><ref>{{Pubmed|11347722|Haddad PM. Antidepressant discontinuation syndromes. Drug Saf. 2001;24(3):183-97}}</ref>:
 
:*'''Day 1:''' reduce dosage of venlafaxine to 75 mg/day.  
 
:*'''Day 1:''' reduce dosage of venlafaxine to 75 mg/day.  
 
:* '''Day 15:''' reduce dosage of venlafaxine to 37.5 mg/day.  
 
:* '''Day 15:''' reduce dosage of venlafaxine to 37.5 mg/day.  
 
:* '''Day 29:''' stop administration of venlafaxine.
 
:* '''Day 29:''' stop administration of venlafaxine.
 
}}
 
}}

Latest revision as of 10:29, 19 July 2011

Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine


Nietinrijdenbord.png Stop venlafaxine
  • In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.[1][2]
  • Another, more risky, possibility is being at a certain dose to use the following scheme:
  • 150 mg/day [3][4][5]:
  • Day 1: reduce dosage of venlafaxine to 75 mg/day.
  • Day 15: reduce dosage of venlafaxine to 37.5 mg/day.
  • Day 29: stop administration of venlafaxine.



  1. The UK Drug and Therapeutics Bulletin; 1999;37:49-52
  2. Editor: please note that not all dosages are available in pharmacy. So now and then you should be creative.
  3. Bazire S, Psychotropic Drug Directory 2010. Aberdeen: HealthComm UK Ltd; 2010.
  4. Fava M et al. Emergence of adverse events following discontinuation of treatment with extended-release venlafaxine. Am J Psychiatry. 1997 Dec;154(12):1760-2
  5. Haddad PM. Antidepressant discontinuation syndromes. Drug Saf. 2001;24(3):183-97
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