Switch medication from trazodone to amitriptyline.
- Before day 0: gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.
- Day 1: reduce dosage of trazodone to 100 mg/day.
- Day 8: stop administration of trazodone.
No wash-out period is needed.
- Day 1: simultaneously start administration of amitriptyline in a dosage of 25 mg/day.
- Day 8: continue administration of amitriptyline in a dosage of 50 mg/day.
- Start low, go slow.
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