Difference between revisions of "Trazodone-bupropion"

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| to = bupropion  
 
| to = bupropion  
 
| stop =  
 
| stop =  
* '''Before day 1:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.
+
{{stopTrazodone}}
* '''Day 1:''' reduce dosage of trazodone to 75-100 mg/day.
 
* '''Day 8:''' stop administration of trazodone.
 
 
| start =  
 
| start =  
 
* A wash-out period is not necessary, but care is needed.
 
* A wash-out period is not necessary, but care is needed.
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| info =  
 
| info =  
 
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes trazodone.
 
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes trazodone.
| info =
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{{trazoTablet}}  
* The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given.
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}}
{{review}} }}
 

Latest revision as of 12:36, 4 November 2015

Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone
Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion

Switch medication from trazodone to bupropion.

Nietinrijdenbord.png Stop trazodone
  • Before day 1: gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.
  • Day 1: reduce dosage of trazodone to 100 mg/day.
  • Day 3: reduce dosage of trazodone to 50 mg/day.
  • Day 8: stop administration of trazodone.
Eenrichtingbord.png Start bupropion
  • A wash-out period is not necessary, but care is needed.
  • Day 8: start administration of bupropion in a normal dosage of 150 mg/day.
  • Day 15: increase dosage of bupropion to 300 mg/day.
Infobord.png More information
  • Bupropion is a strong inhibitor of CYP2D6, which metabolizes trazodone.
  • The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given.
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