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Trazodone-escitalopram

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#redirect [[Trazodone-citalopram]]
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{{ Drugswitch
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| from = trazodone
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| to = escitalopram
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| stop =
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* '''Before day 1:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.
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* '''Day 1:''' reduce dosage of trazodone to 75-100 mg/day.
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* '''Day 8:''' stop administration of trazodone.
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| start =
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* A wash-out period is not necessary, but care is needed.
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* '''Day 8:''' start administration of escitalopram in a normal dosage of 10 mg/day.
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| info =
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* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
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* Escitalopram is a weak inhibitor of CYP2D6, which metabolizes trazodone.
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* The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given. 
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}}

Revision as of 22:54, 4 March 2010

Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone
Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram

Switch medication from trazodone to escitalopram.

Nietinrijdenbord.png Stop trazodone
Eenrichtingbord.png Start escitalopram
Infobord.png More information
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