Difference between revisions of "Escitalopram-moclobemide"
From Psychiatrienet
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Revision as of 14:19, 21 October 2015
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Switch medication from escitalopram to moclobemide.[1] [2]
- Before day 1: gradually reduce dosage of escitalopram to a maximum of 10 mg/day, when this dosage is >10 mg/day.
- Day 1: reduce dosage of escitalopram to a maximum of 5 mg/day.
- Day 8: stop administration of escitalopram.
- Day 8-22: a wash-out period of 2 weeks is necessary.
- Day 23: start administration of moclobemide in normal dosage of 300 mg/day.
- Occurrence of the serotonin syndrome is possible without wash-out period.
- This switch is currently being reviewed.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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