Difference between revisions of "Mirtazapine-duloxetine"

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| from = mirtazapine  
 
| from = mirtazapine  
 
| to = duloxetine  
 
| to = duloxetine  
| stop =  
+
| stop = {{StopSSRI,SNRI}}
* '''Day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.
+
| start = {{StartAntidepressant}}
* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.
+
| info =
| start =  
+
* Safe target dose duloxetine = 60 mg
* '''Day 1:''' simultaneously start duloxetine in a normal dosage of 60 mg/day.
+
}}
* '''Day 8:''' stop administration of mirtazapine and only continue administration of duloxetine. }}
 

Latest revision as of 13:08, 30 June 2023

Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine
Duloxetine
Type Antidepressant
Group SNRI
links
Medscape Duloxetine
PubChem 60835
PubMed Duloxetine
Kompas (Dutch) Duloxetine
Wikipedia Duloxetine

Switch medication from mirtazapine to duloxetine.[1] [2]

Nietinrijdenbord.png Stop mirtazapine
  • Day 1: Decrease dose to 50%
  • Day 8: Stop
Eenrichtingbord.png Start duloxetine
  • Day 1: Start with 50% of the target dose
  • Day 8: Increase dose to 100% of the target dose
  • Day 9 and after: Gradually increase dose as necessary
Infobord.png More information
  • Safe target dose duloxetine = 60 mg
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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