* '''Before day 1:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.{{TCAdecrease25p3d}}| start = No wash-out period is needed.* '''Day 1:''' simultaneously start administration of doxepin in a dosage of 25 mg/day. * '''Day 8:''' stop administration of mirtazapine and continue administration of doxepin. If necessary, increase dosage of doxepin.* "Start low, go slow" is not required, but caution is necessary.{{TCAincrease25p3d}}