Difference between revisions of "Mirtazapine-moclobemide"

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| to = moclobemide  
 
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* '''Day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.
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{{Generaldecrease25p3d}}
* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.
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{{7dWashout}}
* '''Day 8:''' stop administration of mirtazapine.
 
 
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* '''Day 8-14:''' a wash-out period of one week is necessary.
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{{MAOIncrease25p}}
* '''Day 15:''' start administration of moclobemide in a normal dosage of 300 mg/day.
 
 
| info =  
 
| info =  
* Occurrence of serotonin syndrome is not very likely. For safety reasons a wash-out period (of one week) is considered.}}
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* Occurrence of serotonin syndrome is not very likely. For safety reasons a wash-out period (of one week) is considered.
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Latest revision as of 13:49, 16 June 2016

Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine
Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from mirtazapine to moclobemide.[1] [2]

Nietinrijdenbord.png Stop mirtazapine
  • Decrease with about 25% of original dose every 3 days
  • Stop and wait 7 days for washout
Eenrichtingbord.png Start moclobemide
  • Start at the first day after the washout period with about 25% of target dose.
Infobord.png More information
  • Occurrence of serotonin syndrome is not very likely. For safety reasons a wash-out period (of one week) is considered.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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