Difference between revisions of "Nortriptyline-tranylcypromine"

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| to = tranylcypromine  
 
| to = tranylcypromine  
 
| stop =  
 
| stop =  
* '''Before day 0:''' gradually reduce dosage of nortriptyline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
+
{{TCAdecrease25p3d}}
* '''Day 1-3:''' reduce dosage of nortriptyline to 25 mg/day.
 
* '''Day 4-7:''' reduce dosage of nortriptyline to 10 mg/day.
 
* '''Day 8:''' stop administration of nortriptyline.
 
 
| start =  
 
| start =  
* '''Day 8-14:''' a wash-out period of one week is necessary.
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{{Starttranyl}}
* '''Day 15:''' start administration of tranylcypromine in a normal dosage of 20 mg/day.}}
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| info =
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{{nowashout}}<ref name="informatorium">{{KNMP}}</ref>
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}}

Latest revision as of 14:17, 8 March 2024

Nortriptyline
Type Antidepressant
Group TCA
links
Medscape Nortriptyline
PubChem 4543
PubMed Nortriptyline
Kompas (Dutch) Nortriptyline
Wikipedia Nortriptyline
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from nortriptyline to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop nortriptyline
  • Day 1: Decrease with about 25% of the original dose per 3 days.
Eenrichtingbord.png Start tranylcypromine
  • Start tranylcypromine in a low dosage of 20 mg/day for one week.
  • After this week the dosage of tranylcypromine can be increased.
Infobord.png More information
  • No wash-out period is necessary[3]
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. KNMP; Informatorium Medicamentorum 2023; Monografie "{{{1}}}" (Dutch)
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