Difference between revisions of "Bupropion-moclobemide"
From Psychiatrienet
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* '''Day 8:''' start moclobemide with 150 mg/day. | * '''Day 8:''' start moclobemide with 150 mg/day. | ||
* '''Day 12:''' increase moclobemide to 300 mg/day. | * '''Day 12:''' increase moclobemide to 300 mg/day. | ||
| + | * '''Day 15:''' if necessary, increase moclobemide to 600 mg/day. | ||
}} | }} | ||
Revision as of 07:53, 23 July 2009
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Switch medication from bupropion to moclobemide.[1] [2]
Stop bupropion - Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.
- When a dosage of 150 mg/day is reached, stop administration.
Start moclobemide- Day 1-7: wash-out period of one week is necessary.
- Day 8: start moclobemide with 150 mg/day.
- Day 12: increase moclobemide to 300 mg/day.
- Day 15: if necessary, increase moclobemide to 600 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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