Difference between revisions of "Duloxetine-mirtazapine"

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(Created page with '{{Drugswitch | from = duloxetine | to = mirtazapine | stop = * '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day. * '''Day 1:''' reduce a dosage o...')
 
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* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
 
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
 
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
 
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
 +
* '''Day 8:''' stop administration of duloxetine.
 
| start =   
 
| start =   
* '''Day 1:''' simultaneously start mirtazapine in a normal dosage of 15-30 mg/day.
+
* '''Day 8:''' start mirtazapine in a normal dosage of 15-30 mg/day.
* '''Day 8:''' stop administration of duloxetine and continue with mirtazapine only. }}
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* '''Day 15:''' if necessary increase mirtazapine.  
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}}

Revision as of 08:23, 4 August 2009

Duloxetine
Type Antidepressant
Group SNRI
links
Medscape Duloxetine
PubChem 60835
PubMed Duloxetine
Kompas (Dutch) Duloxetine
Wikipedia Duloxetine
Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine

Switch medication from duloxetine to mirtazapine.[1] [2]

Nietinrijdenbord.png Stop duloxetine
  • Day 0: gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
  • Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
  • Day 8: stop administration of duloxetine.
Eenrichtingbord.png Start mirtazapine
  • Day 8: start mirtazapine in a normal dosage of 15-30 mg/day.
  • Day 15: if necessary increase mirtazapine.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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