Difference between revisions of "Moclobemide-imipramine"
From Psychiatrienet
(Created page with '{{Drugswitch | from = moclobemide | to = imipramine | stop = * Gradually reduce dosage of moclobemide to a maximum of 300 mg/ day. * When a dosage of 300 mg/day is reached, ...') |
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| to = imipramine | | to = imipramine | ||
| stop = | | stop = | ||
| − | * | + | * '''Before day 0:''' gradually reduce dosage of moclobemide to a maximum of 300 mg/day. |
| − | * | + | * '''Day 1:''' reduce the dosage of moclobemide to 150 mg/day. |
| + | * '''Day 8:''' stop administration of moclobemide. | ||
| start = | | start = | ||
| − | + | No wash-out period is needed. | |
| − | * | + | * '''Day 9:''' start administration of imipramine the next day in a normal dosage of 25-75 mg/day.}} |
Revision as of 15:12, 7 May 2009
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Switch medication from moclobemide to imipramine.[1] [2]
Stop moclobemide - Before day 0: gradually reduce dosage of moclobemide to a maximum of 300 mg/day.
- Day 1: reduce the dosage of moclobemide to 150 mg/day.
- Day 8: stop administration of moclobemide.
Start imipramineNo wash-out period is needed.
- Day 9: start administration of imipramine the next day in a normal dosage of 25-75 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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