Mirtazapine-venlafaxine

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Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine
Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine

Switch medication from mirtazapine to venlafaxine.[1] [2]

Nietinrijdenbord.png Stop mirtazapine
  • Day 1: reduce dosage of mirtazapine to a maximum of 30 mg/day.
  • Day 7: reduce to 15 mg/day.
  • Day 14: stop administration.
Eenrichtingbord.png Start venlafaxine
  • Day 14: start venlafaxine in a normal dosage of 37, mg or 75 mg (slow realease)/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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