Zuclopenthixol MA-Fluphenazine LA

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Zuclopenthixol
Medium long acting
Type Antipsychotic
Group Thioxanthenes
links
PubChem 5311507
PubMed Zuclopenthixol
Kompas (Dutch) Zuclopenthixol
Wikipedia Zuclopenthixol
Fluphenazine
long acting
Type Antipsychotic
Group Phenothiazines
links
Medscape Fluphenazine
PubChem 3372
PubMed Fluphenazine
Kompas (Dutch) Fluphenazine
Wikipedia Fluphenazine

Switch medication from Zuclopenthixol_MA to Fluphenazine_LA.[1] [2]

Nietinrijdenbord.png Stop Zuclopenthixol_MA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Fluphenazine_LA
  • Day 1: Start depot according general dosing advice (Dotted line in graph)
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[3]
    StopDepotZucloMAStartDepot.jpg
Nietinrijdenbord.png — Zuclopenthixol_MA
Eenrichtingbord.png — Fluphenazine_LA


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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