Switch medication from agomelatine to fluoxetine.
- Day 1: Stop agomelatine.
- Agomelatine can be stopped abruptly for every dosage.
- Day 2: Start administration of fluoxetine in a dosage of 20 mg/day.
- After 3 weeks: If necessary, gradually increase dosage of fluoxetine to max. 60 mg/day
- A wash-out period is not necessary.
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