Difference between revisions of "Amisulpride-Lurasidone"

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{{Drugswitch  
 
{{Drugswitch  
 
| from = Amisulpride
 
| from = Amisulpride
| to = Lurasidon
+
| to = Lurasidone
| stop =  
+
| stop = {{StopStand}}
* '''Day 1-7:''' gradually reduce the dose of amisulpride to 50% of the dose.
+
| start = {{StartStand}}
* '''Day 8-14:''' gradually reduce the dose of amisulpride to 0% of the dose
+
| info =
* '''Day 14:''' stop administration of amisulpride.
+
| view = switchstandaardup en down.jpg
| start =
+
 
* '''Day 1-7:''' start administration of lurasidon in a dose of 40 mg/day.
+
 
* '''Day 8-14:''' increase the dose of lurasidon to 80 mg/day if necessary. Note: Continue the dose of lurasidone 40 mg/day if the patiënt is stable.<ref>[http://www.ncbi.nlm.nih.gov/pubmed/23473350 McEvoy JP et al. Effectiveness of lurasidone in patients with schizophrenia or schizoaffective disorder switched from other antipsychotics: a randomized, 6-week, open-label study.J Clin Psychiatry. 2013 Feb;74(2):170-9.]</ref>   
+
<ref>[http://www.ncbi.nlm.nih.gov/pubmed/23473350 McEvoy JP et al. Effectiveness of lurasidone in patients with schizophrenia or schizoaffective disorder switched from other antipsychotics: a randomized, 6-week, open-label study.J Clin Psychiatry. 2013 Feb;74(2):170-9.]</ref>   
 
| info = {{caveQT}}
 
| info = {{caveQT}}
 
}}
 
}}

Revision as of 15:02, 16 March 2015

Amisulpride
Type Antipsychotic
Group Atypical AP
links
PubChem 2159
PubMed Amisulpride
Wikipedia Amisulpride
Lurasidone
Type Antipsychotic
Group Atypical AP
links
Medscape Lurasidone
PubMed Lurasidone
Kompas (Dutch) Lurasidone
Wikipedia Lurasidone

Switch medication from Amisulpride to Lurasidone.

Nietinrijdenbord.png Stop Amisulpride
  • Day 1-4: approx. 75% of initial dose
  • Day 5-8: approx. 50% of initial dose
  • Day 9-12: approx. 25% of initial dose
  • Day 13: stop
Eenrichtingbord.png Start Lurasidone
  • Day 1-4: approx. 25% of target dose
  • Day 5-8: approx. 50% of target dose
  • Day 9-12: approx. 75% of target dose
  • Day 13: target dose
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[1]
    [[File:switchstandaardup en down.jpg


[2]]]

Nietinrijdenbord.png — Amisulpride
Eenrichtingbord.png — Lurasidone


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