Amitriptyline-imipramine

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Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline
Imipramine
Type Antidepressant
Group TCA
links
Medscape Imipramine
PubChem 3696
PubMed Imipramine
Kompas (Dutch) Imipramine
Wikipedia Imipramine

Switch medication from amitriptyline to imipramine.

Nietinrijdenbord.png Stop amitriptyline
  • Decrease with about 25% of the original dose per 3 days.
Eenrichtingbord.png Start imipramine
  • No wash-out period is needed.
  • Increase with about 25% of target dose per 3 days.
Infobord.png More information
  • Both drugs are a TCA with anticholinergic properties, so a switch to a relatively high starting dose can be made.
  • Plasma monitoring for TCA's is advisable, because of plasma-reponse relations, genetic polymorphism and under or overdosing.[1]
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