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Bupropion-escitalopram

Revision as of 07:55, 14 October 2015 by Anoek (talk | contribs)
Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram

Switch medication from bupropion to escitalopram.[1] [2]

Nietinrijdenbord.png Stop bupropion
  • Before day 1: Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.
  • Day 1: Stop administration of bupropion
Eenrichtingbord.png Start escitalopram
  • Day 2: Start escitalopram with the dosage of 10 mg/day.
  • After 3 weeks: If necessary, increase dosage to 20 mg/day.
Infobord.png More information
  • No wash-out period is needed.
  • Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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