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Type Antidepressant
Group other
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Type Antidepressant
Group MAO-I
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from bupropion to moclobemide.

Nietinrijdenbord.png Stop bupropion
  • Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.
  • When a dosage of 150 mg/day is reached, stop administration.
Eenrichtingbord.png Start moclobemide
  • Day 1-7: wash-out period of one week is necessary.
  • Day 8: start moclobemide with 150 mg/day.
  • Day 12: increase moclobemide to 300 mg/day.
  • Day 15: if necessary, increase moclobemide to 600 mg/day.
Letopbord.png Cave
  • Occurrence of the serotonin syndrome is possible without wash-out period.
  • This switch is currently being reviewed.

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