Difference between revisions of "Citalopram-agomelatine"

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{{ Drugswitch  
 
{{ Drugswitch  
| from = escitalopram
+
| from = citalopram
 
| to = agomelatine  
 
| to = agomelatine  
 
| stop =  
 
| stop =  
* '''Before day 0:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 40 mg/day, resp. 20 mg/day.
+
{{stopCitalopram14d}}
* '''Day 1:''' reduce dosage of citalopram/escitalopram to 20 mg/day, resp. 10 mg/day.
 
* '''Day 8:''' stop administration of citalopram/escitalopram.
 
  
 
| start =  
 
| start =  
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.
+
* '''Day 16:''' start administration of agomelatine in a dosage of 25 mg/day.
* '''Day 8:''' only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day. }}
+
* '''Day 23:''' if necessary, increase dosage of agomelatine to 50 mg/day.  
 +
<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>
 +
 
 +
|info=
 +
{{SSRI14d}}
 +
}}

Latest revision as of 14:27, 21 October 2015

Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine

Switch medication from citalopram to agomelatine.

Nietinrijdenbord.png Stop citalopram
  • Day 1: reduce dosage of citalopram to a maximum of 20 mg/day
  • Day 8: reduce dosage of citalopram to 10 mg/day
  • Day 15: stop citalopram
Eenrichtingbord.png Start agomelatine
  • Day 16: start administration of agomelatine in a dosage of 25 mg/day.
  • Day 23: if necessary, increase dosage of agomelatine to 50 mg/day.

[1]

Infobord.png More information
  • The reduction of the SSRI doses in 7-14 days could cause emotional instability, headache and flu-like symptoms. One could extend this period.
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