Citalopram-agomelatine

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Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine

Switch medication from citalopram to agomelatine.[1] [2]

Nietinrijdenbord.png Stop citalopram
  • Before day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 40 mg/day, resp. 20 mg/day.
  • Day 1: reduce dosage of citalopram/escitalopram to 20 mg/day, resp. 10 mg/day.
  • Day 8: reduce dosage of citalopram/escitalopram to 10 mg/day, resp. 5 mg/day.
  • Day 15: stop administration of citalopram/escitalopram.
Eenrichtingbord.png Start agomelatine
  • Day 1: simultaneously start administration of agomelatine in a dosage of 25 mg/day.
  • Day 15: only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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