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Type Antidepressant
Group SSRI
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Type antidepressant
Group TCA
ATC-code N06AA16
PubChem 13473
PubMed dosulepin
Kompas (Dutch) dosulepin
Wikipedia dosulepin

Switch medication from citalopram to dosulepine.

Nietinrijdenbord.png Stop citalopram
  • Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
  • Day 1: reduce dosage of citalopram/escitalopram to a maximum of 10 mg/ day resp. 5 mg/day.
Eenrichtingbord.png Start dosulepine
  • Day 1: simultaneously start administration of dosulepine in a normal dosage of 50-75 mg/day.
  • Day 8: stop administration of citalopram/escitalopram and continue administration of dosulepine only.
Infobord.png More information
  • “Start low, go slow” for dosulepine is not required, but caution is necessary.
  • The same applies to escitalopram.
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. 1.0 1.1 1.2 1.3 1.4 KNMP; Informatorium Medicamentorum 2015; Monografie "dosulepine" (Dutch)
  2. NVZA;; Monografie 63 (dutch)
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