Difference between revisions of "Citalopram-duloxetine"
From Psychiatrienet
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| from = citalopram | | from = citalopram | ||
| to = duloxetine | | to = duloxetine | ||
| − | | stop = | + | | stop = {{StopEscitalopram}} |
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| start = | | start = | ||
* '''Day 8:''' start administration of duloxetine in a dosage of 30 mg/day. | * '''Day 8:''' start administration of duloxetine in a dosage of 30 mg/day. | ||
* '''Day 15:''' increase dosage of duloxetine 60 mg/day. | * '''Day 15:''' increase dosage of duloxetine 60 mg/day. | ||
| info = | | info = | ||
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* {{theorSS}} | * {{theorSS}} | ||
}} | }} | ||
Revision as of 22:17, 4 March 2010
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Switch medication from citalopram to duloxetine.[1] [2]
Stop citalopram - Before day 1: gradually reduce dosage of escitalopram to a maximum of 10 mg/day, when this dosage is >10 mg/day.
- Day 1: reduce dosage of escitalopram to a maximum of 5 mg/day.
- Day 8: stop administration of escitalopram.
Start duloxetine- Day 8: start administration of duloxetine in a dosage of 30 mg/day.
- Day 15: increase dosage of duloxetine 60 mg/day.
More information- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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